The duration of hospitalization was significantly shorter in the F group compared to the NF group. Conclusion: Our findings demonstrated
that clinical characteristics other than CKD-MBD at hemodialysis initiation were similar between very elderly patients and younger patients with ESRD. Furthermore, CX-4945 datasheet appropriate management by nephrologists may lead the improvement of quality of life for very elderly patients with ESRD. WANG JI-WEI1, ZHANG LING2, LI MINGZI3, CHEN JIN-BOR4, CHENG BEN-CHUNG5, CHEN TUN-LING6, TSENG TA-CHUAN7 1Division of Nephrology, Jilin City Central Hospital, Yanbian University Medical College; 2Division of Nephrology, China-Japan Friendship Hospital, China; 3Division of Nephrology, Jilin City Central Hospital, Yanbian University
Medical College, China; 4Division of Nephrology, Selleckchem Galunisertib Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; 5Division of Nephrology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; 6Bo Da Ling Zheng (Bj) Hospital Investment Management Consulting Limited Inc. China; 7Bo Da Ling Zheng (Bj) Hospital Investment Management Consulting Limited Inc. China Introduction: Hyperparathyroidism is an impact factor for cardiovascular disease in dialysis patients. However, there are limited data pertaining the severity of hyperparathyroidism and cardiac function in dialysis patients. The purpose of present study was to explore the influence of severity of hyperparathyroidism on cardiac function in dialysis patients. Methods: The study design
was a retrospective, parallel-group, cross-sectional cohort study. The enrolled patients were chronic dialysis patients either on hemodialysis or peritoneal dialysis in two hospitals. A total 106 subjects were recruited, men: women were 53:53. The comparable variables included blood levels of Ca, P, Ca-P product, iPTH and parameters of cardiac echography. IKBKE The study subjects were stratified into two groups according to cutoff iPTH level 800 pg/mL. Results: In severe group, the mean age was 48.8 years, dialysis duration was 105.2 months, mean iPTH level was 1552.2 pg/mL. In mild group, the mean age was 50.4 years, dialysis duration was 33.0 months (P < 0.0001), and mean iPTH level was 353 pg/mL (P < 0.0001). The Ca/P profiles were Ca 2.6: 2.2 mmol/L (P < 0.0001), P 2.1: 1.5 mmol/L (P < 0.0001), Ca-P product 5.4: 3.4 (P < 0.0001). The significant variables in cardiac echography were left atrium diameter 43.1: 34.3 mm (P < 0.0001), ejection fraction 64.6: 59.3% (P = 0.031). The other variables including left ventricle end-systolic volume, end-diastolic volume, aortic root diameters, interventricular septum thickness were not statistical significance between two groups.