7 mature oocytes were available for fertilization/patient. The fertilization rate was 77.8%, resulting in 4.5 +/- 2.7 vitrified embryos/patient. The median duration from the first evaluation to oocyte retrieval was 13 days. Calculated pregnancy rates per vitrified oocyte and embryo were 3.8% and 8.1%, respectively. IVM can be considered a useful option for fertility preservation in breast-cancer patients. (C) 2010, Reproductive Healthcare Ltd. Published by Elsevier

Ltd. All rights reserved.”
“BACKGROUND: Postpartum hematomas are a potentially serious obstetric complication for which management options are not standardized. We report successful treatment of a large postpartum hematoma using arterial embolization as primary approach.

CASE: A 29-year-old woman at term gestation underwent vacuum-assisted vaginal delivery. Two hours later, marked rectal pain developed. Examination revealed a large left vaginal hematoma and no Nutlin3a obvious bleeding sites. Computed tomography demonstrated a 10-cm supralevator hematoma and extrauterine arterial bleeding. Angiography revealed contrast extravasation from a branch of the left internal pudendal artery. Selective

embolization of this branch stopped the bleeding. The patient was discharged on the third postpartum day. Eight weeks after delivery, there was no evidence of the hematoma.

CONCLUSION: Arterial embolization can be used as a first-line treatment for large postpartum PCI-34051 nmr hematomas.”
“Polycystic ovary syndrome (PCOS) is strongly associated with metabolic abnormalities in Western women. However, data from other populations and geographical regions are scarce. This study evaluated cardiovascular and metabolic risk factors in Chinese Pexidartinib infertile women diagnosed with PCOS using the 2003 Rotterdam consensus criteria. A total of 615

women representing the four PCOS phenotypes (oligo- or anovulation (AO) + hyperandrogenism (HA) + polycystic ovaries (PCO), AO + HA, AO + PCO and HA + PCO) underwent standardized metabolic screening including a 75 g oral glucose tolerance test. All groups presented with similar reproductive characteristics, with the only difference being a significantly higher Ferriman-Gallwey score for hirsutism (P = 0.01) in the subgroup characterized by HA + PCO. Overall, the prevalence of metabolic syndrome was 6.4%, with no difference among the four groups (range of 2.3-12.2%). Metabolic syndrome was associated with body mass index (P < 0.001), waist/hip ratio (P = 0.002), index of insulin resistance (P = 0.005) and fasting insulin (P = 0.009) in multivariate analysis. Compared with Caucasians and Chinese women in Westernized societies, mainland Chinese women with PCOS have a low risk of metabolic syndrome and its presence does not vary across the specific PCOS phenotypes. (C) 2010, Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.”
“BACKGROUND: Oxidized regenerated cellulose is a topical hemostatic agent that is used commonly in abdominal and pelvic surgery.

Males show a severe form of this disease, while females often manifest mild to moderate symptoms. We identified a missense mutation (c.463C>T) in the EDA gene in a Jordanian family, using direct DNA sequencing. This mutation leads to an amino acid change of arginine to cysteine selleck chemical in the extracellular domain of ectodysplasin-A,

a protein encoded by the EDA gene. The phenotype of a severely affected 11-year-old boy with this mutation included heat intolerance, sparse hair (hypotrichosis), absence of 17 teeth (oligodontia), speech problems, and damaged eccrine glands, resulting in reduced sweating (anhidrosis). Both the mother (40 years old) and the sister (10 years old) were carriers with mild to moderate symptoms of this disease, while the father was healthy. This detailed description of the phenotype caused by this missense mutation could be useful for prenatal diagnosis.”
“Background: Studies of glycoconjugate selleck inhibitor vaccines have traditionally used an immune challenge with a plain polysaccharide vaccine to demonstrate immunologic memory. Plain polysaccharide vaccines are poorly immunogenic in children and can induce subsequent immunologic hyporesponsiveness. We therefore assessed the use of glycoconjugate vaccines as an alternative method of demonstrating immunologic memory.

Methods: Children immunized with hepatitis B vaccine or serogroup C meningococcal glycoconjugate vaccine (MenCC) at age 2, 3, 4 months received a plain polysaccharide

meningococcal serogroup A/C vaccine (MenACP) or MenCC at age 12 months. A post hoc analysis of serum bactericidal activity responses to MenCC assessed whether this differed in MenCC primed and MenCC naive infants.

Results: click here MenCC primed children displayed higher geometric mean serum bactericidal titers

than MenCC naive children following MenACP (1518 compared with 30; P = 0.003). A similar difference was seen after a dose of MenCC to toddlers (MenCC primed: 8663, MenCC naive: 710; P < 0.001). The latter comparison became a borderline significance after adjusting for higher pretoddler immunization serum bactericidal geometric mean titers in the MenCC primed group (P = 0.068).

Conclusions: Administration of glycoconjugate vaccines provides an important alternative method of demonstrating immunologic memory, avoiding the use of plain polysaccharide vaccines that are potentially deleterious in children. This has implications for the design of all future clinical trials of glycoconjugate vaccines.”
“Objective-To evaluate the clinical response rate, progression-free survival time, overall survival time, and possible prognostic factors associated with a cyclophosphamide-, vincristine-, and prednisone (COP)-based chemotherapy protocol in cats with lymphoma.

Design-Retrospective case series.

Animals-114 cats with lymphoma.

Procedures-Medical records-of cats receiving a weekly COP-based chemotherapy protocol from 1998 to 2008 at the Matthew J.

A body of evidence is not

rated up in quality if studies yield consistent results, but may be rated down in quality if inconsistent. Criteria for evaluating consistency include similarity Blebbistatin mouse of point estimates, extent of overlap of confidence intervals, and statistical criteria including tests of heterogeneity and I(2). To explore heterogeneity, systematic review authors should generate and test a small number of a priori hypotheses related to patients, interventions, outcomes, and methodology. When inconsistency is large and unexplained, rating down quality for inconsistency is appropriate, particularly if some studies suggest substantial benefit, and others no effect or harm (rather than only large vs. small effects).

Apparent subgroup effects may be spurious. Credibility is increased if subgroup effects are based on a small number of a priori hypotheses with a specified direction; subgroup comparisons come from within rather than between studies; tests of interaction generate low P-values; and have a biological rationale. (C) 2011 Elsevier Inc. All rights reserved.”
“House calls provide a unique perspective on patients’ environment and health problems. The demand for house calls is selleck inhibitor expected to increase considerably in future decades as the U.S. population ages. Although study results

have been inconsistent, house calls involving multidisciplinary teams may reduce hospital readmissions and long-term care facility stays. Common

indications for house calls are management of acute or chronic illnesses, and palliative care. Medicare beneficiaries must meet specific criteria to be eligible for home health services. The INHOMESSS mnemonic provides a checklist for components of a comprehensive house call. In addition to performing a clinical assessment, house calls may involve observing the patient performing daily activities, reconciling medication discrepancies, and evaluating home safety. House learn more calls can be integrated into practice with careful planning, including clustering house calls by geographic location and coordinating visits with other health care professionals and agencies. (Am Fam Physician. 2011;83(8):925-931. Copyright (c) 2011 American Academy of Family Physicians.)”
“Direct evidence comes from research that directly compares the interventions in which we are interested when applied to the populations in which we are interested and measures outcomes important to patients. Evidence can be indirect in one of four ways. First, patients may differ from those of interest (the term applicability is often used for this form of indirectness). Secondly, the intervention tested may differ from the intervention of interest. Decisions regarding indirectness of patients and interventions depend on an understanding of whether biological or social factors are sufficiently different that one might expect substantial differences in the magnitude of effect.

Aspirin is used as thromboprophylactic agent in approximately 25% of patients undergoing total hip and total knee arthroplasty in year 2006 in England and Wales. There is no difference in mortality in these patients compared to patients on other pharmacological agents.

There is conflicting evidence and differences

in interpretation of the data from the literature. If specific outcome measures and complications such as symptomatic DVT, PE and bleeding were logged in arthroplasty registers, the resulting data would be useful in individualised decision-making.”
“The CCAAT/enhancer-binding proteins Selleckchem VS-4718 (C/EBPs) are a family of leucine-zipper transcription factors that regulate gene expression to control cellular proliferation, differentiation, inflammation and metabolism. Encoded by an intronless gene, C/EBP beta is expressed as several distinct protein isoforms (LAP1, LAP2, LIP) whose expression is regulated by the differential use of several in-frame translation start

sites. LAP1 and LAP2 are transcriptional activators and are associated with differentiation, whereas LIP is frequently elevated in proliferative tissue and acts as a dominant-negative inhibitor of transcription. However, emerging evidence suggests that LIP can serve as a transcriptional activator in some cellular contexts, and that LAP1 and LAP2 might also have unique actions. selleckchem The LIP: LAP ratio is crucial for the maintenance of normal growth and development, and increases in this ratio lead to aggressive forms of breast cancer. This review discusses the regulation of C/EBPb activity by post-translational modification, the individual actions of LAP1, LAP2 and LIP, and the functions and downstream targets that are unique to each isoform. The role of the C/EBP beta isoforms in breast cancer is discussed and emphasis is placed on their interactions with receptor tyrosine kinases.”
“The leaching process of copper and zinc from copper converter

slag with ferric iron in sulfuric acid solutions obtained using the association of acidophilic chemolithotrophic microorganisms was investigated. The best parameters of PI3K inhibitor chemical leaching (temperature 70 degrees C, an initial concentration of ferric iron in the leaching solution of 10.1 g/L, and a solid phase content in the pulp of 10%) were selected. Carrying out the process under these parameters resulted in the recovery of 89.4% of copper and 39.3% of zinc into the solution. The possibility of the bioregeneration of ferric iron in the solution obtained after the chemical leaching of slag by iron-oxidizing acidophilic chemolithotrophic microorganisms without inhibiting their activity was demonstrated.”
“Patients with asthma who have persistent symptoms despite treatment with inhaled steroids and long-acting beta agonists are considered to have severe asthma. Omalizumab is a monoclonal antibody directed against IgE, which is used as an add-on treatment for patients who have severe persistent allergic asthma.

9% expressly denied wishing to do so.

The most important barriers were the costs, the unclear benefit and a feared worsening of the doctor-patient-communication during consultation.

Conclusion: IT and especially EMRs are underused in daily ambulatory care in Switzerland. To increase the use of EMRs, several approaches could be helpful. First of all, the benefit

of EMRs in daily routine care have to be increased as, for example, by decision support systems, tools to avoid pharmaceutical interactions and reminder systems to enable a proactive treatment of chronically ill patients. Furthermore, adequate https://www.selleckchem.com/products/BafilomycinA1.html approaches to offer appropriate reimbursement for the financial investments have to considered such as an additional payment for electronically generated, evidence based quality indicators.”
“Purpose: To describe the neuroimaging manifestations of Lyme disease at magnetic resonance (MR) imaging of the brain.

Materials and Methods: Institutional review board approval was obtained and HIPAA compliance was followed. This study retrospectively

reviewed the MR imaging findings of all patients seen from 1993 to 2007 in whom neuro-Lyme disease was suspected and who were referred ICG-001 clinical trial for MR imaging of the brain for the evaluation of neurologic symptoms.

Results: Of 392 patients suspected of having neuro-Lyme disease, 66 patients proved to have the disease on the basis of clinical criteria, serologic results, and response to treatment. Seven of these 66 patients showed foci of T2 prolongation in the cerebral white matter, one had an enhancing lesion with edema, and three demonstrated nerve-root or meningeal enhancement. Of the seven patients with foci of T2 prolongation in the white matter, three were an age at which white matter findings due to small-vessel disease are common.

Conclusion:

In cases of nerve-root or meningeal enhancement, ACY-241 Lyme disease should be considered in the differential diagnosis in the proper clinical setting. (C) RSNA, 2009″
“The redistribution of boron during the formation of the Ni silicides was investigated using atom probe tomography and transmission electron microscopy. A 7 nm amorphous intermixed region was found after deposition of a 30 nm thick Ni film at room temperature. The formation of this Ni-Si layer was found to have almost no influence on the boron implantation profile. After heating at 290 degrees C for 1 h, three types of silicides (Ni(2)Si, NiSi, and NiSi(2)) were identified below a thin remaining film of Ni (8 nm). The unexpected presence of the silicon-rich NiSi(2) phase at this temperature may be caused by the presence of a thin silicon oxide (SiO(2)) observed at the Ni/Ni(2)Si interface that may act as a diffusion barrier. The average boron profile in NiSi(2) and NiSi silicides is similar to the profile in the silicon substrate before reaction. A segregation of boron at several interfaces was detected. Small boron clusters (1.5 at.

Compared with turbo spin-echo imaging, DW imaging had higher sensitivity (76% vs 7%) but slightly lower specificity (94.0% vs 99.5%) for detection of subcentimeter nodal metastases.

Conclusion: DW imaging performed with ADC(b0-1000) values had higher

accuracy than turbo spin-echo MR imaging in nodal staging, providing added value in the detection of subcentimeter nodal”
“This study deals with the degradation of polyethylene terephthalate (PET) waste through aminolysis with various amines. All of these degradation experiments were carried out at ambient temperature and at normal https://www.selleckchem.com/products/CX-6258.html pressure. Although PET is known to be recycled in many ways, but still there is a need of development of other environment friendly recycling techniques. The amines used to study the degradation of PET waste were namely methylamine, ethylamine, and n-butyl amine, respectively where the degradation of PET waste completes in 45 days. The aminolyzed products so obtained were characterized by using various conventional techniques such as spectroscopic techniques namely IR, NMR, and simultaneous differential scanning calorimeter (DSC). In the present research work, a useful method of PET recycling by using various amines was successfully established. (C) 2009 Wiley p53 inhibitor Periodicals, Inc. J Appl Polym

Sci 115: 3074-3080, 2010″
“The systematic study of the defect structure evolution in single crystal

specimens deformed in situ in the high voltage transmission electron microscope (HVTEM) was started around 1977 in the Baikov Metallurgy Institute of the USSR Academy of Sciences. All the experience gathered for the past 30 years has set up the basis for the determination of the way that metals adapt to the different physical factors inside the HVTEM column. In the present work the detailed phenomenology of the check details generation and propagation process of cracks in single crystals of Mo with different crystallographic orientations as well as the kinetics of opening of primary and secondary cracks and the tip evolution for cracks with different dislocation generation sources is presented. (C) 2010 American Institute of Physics. [doi: 10.1063/1.3284090]“
“The present study proposes an agar diffusion microbiological assay for quantitation of the antibiotic doripenem in powder for injection. The method was developed according to official guidelines and its stability-indicating performance was studied by stress testing in pre-defined conditions of heat and UV-C radiation. Based on the response obtained from growth inhibition of a strain of Staphylococcus epidermidis ATCC 12228, the quantitation was carried out in the range of 1.0 – 4.0 mu g ml(-1). The percentage of drug estimated was 99.42% (RSD=3.12%), with satisfactory intra-day and inter-day precision.

We will also review the clinical features of FTD caused by CHMP2B truncation mutations as well as new brain imaging and neuropathological findings. Finally, we collate the current data on CHMP2B missense Cl-amidine mutations, which have been

reported in FTD and motor neuron disease.”
“We prospectively followed-up 32 pediatric patients with cerebral cavernomas (CCs) to better define surgical indications in this population. Three groups of patients were identified: (a) children with macrohemorrhage (21 patients, 65.6%), (b) children with localized or diffuse headache (6 patients, 18.8%) and (c) children with epilepsy (5 patients, 15.6%). Surgery was performed in 28 out of the 32 (87.5%) subjects. New transient post-operative neurological deficits were observed in two children. One child developed a post-operative hematoma. At a median follow-up of 4 years (range 1-11 years), 22 out of the 28 (78.6%) operated patients were in good conditions. All operated subjects with epilepsy were seizure-free. We confirm the high risk of macrohemorrhage in pediatric CCs. Surgery is mostly recommended in accessible cavernomas, except for small, asymptomatic click here deep-seated CCs or for punctuate lesions without bleeding signs.”
“Inclusion body myopathy (IBM) associated with paget’s

disease of the bone (PDB) and fronto-temporal dementia (FTD) or IBMPFD, is a rare multisystem degenerative disorder due to mutations in valosin containing protein (VCP). VCP is a ubiquitously expressed protein that facilitates the degradation of proteins via the

ubiquitin proteasome and autophagy pathways. Affected brain and muscle tissue in IBMPFD have ubiquitinated and TAR DNA binding protein-43 (TDP-43) inclusions. In skeletal muscle, this pathology is consistent with IBM. While in the CNS, IBMPFD is a frontotemporal lobar degeneration with ubiquitinated inclusions (FTLD-U) subtype. Recent studies suggest that IBMPFD mutations in VCP disrupt its function in protein degradation. This review will explore the clinical phenotype check details and pathology of IBMPFD with an emphasis on central nervous system degeneration. In addition, we will discuss the current understanding regarding VCP’s function in terminally differentiated tissue and how disease associated mutations result in both myo- and neurodegeneration.”
“This article compares the important differences in the American College of Cardiology Foundation (ACCF)/A-merican Heart Association (AHA)/Heart Rhythm Society (HRS), Canadian Cardiovascular Society (CCS), and European Society of Cardiology (ESC) 2010 guidelines on atrial fibrillation (AF). All guidelines recommend more lenient targets for ventricular rate control although the CCS guidelines recommend a target heart rate at rest <100 bpm whereas the the ACCF/AHA/HRS and ESC guidelines accept a target heart rate at rest <110 bpm with provisos.

7 vs 2.5 g/kg diet) and CH5183284 price three others containing a low available P but supplemented with 250, 500 and 12,500 units of phytase (FTU) per kg diet, respectively, were prepared. Each diet was fed ad libitum to birds in six metabolism cages (five birds in each cage) in a randomised block

design. It was found that birds fed a high (12,500 ETU) dosage of phytase grew faster (P < 0.001) and retained proportionally more carotenoids in the liver (P < 0.05) compared to birds fed unsupplemented diet. The results suggest that dietary phytase may improve the anti-oxidative status of birds fed low P diets through enhancing dietary carotenoid availability. (C) 2010 Elsevier Ltd. All rights reserved.”
“The aim of this study was to evaluate the gastrointestinal parasitism in Cavia aperea aperea (cavy), captured in the central region of Rio Grande do Sul State. Fecal samples from five free-living cavies were collected for research of parasites. Samples were analyzed by the centrifugal-flotation method with zinc sulfate and parasites were identified microscopically based on (oo)cyst and egg size and morphology. Cysts of Giardia sp. and (oo)cysts of Cryptosporidium sp. and Cystoisospora sp. were observed in one or more cavies. Eggs of Paraspidodera uncinata were observed in three of the five rodents. All infected animals showed mild infection by parasite. This is the first report of Giardia sp., Cryptosporidium sp. and Cystoisospora sp. in Cavia a.

aperea. (C) 2010 Elsevier Ltd. All rights reserved.”
“From September 2008 to April 2009 several cases of spontaneous bleeding and nodules from LY2835219 the back and withers

area of cattle otherwise considered as healthy have been reported from several farms in southwestern and southern Germany. Successive investigation of these cases gave strong evidence of Parafilaria (P.) bovicola infections due to their seasonal occurrence and specific pathological lesions. There was no history of animal import from endemic countries for the affected cattle herds. In AL3818 nmr one case, a nodule containing nematode fragments and an intact female nematode were recovered from a slaughtered White Galloway bull. This sample was identified as P. bovicola and is the first report of bovine parafilariosis in Germany. (C) 2010 Elsevier Ltd. All rights reserved.”
“There are different protocols of molecular diagnosis methods available including DNA extraction methods to diagnose of Toxoplasma gondii, being necessary to perform comparative studies in biological samples. The aim of this study is to compare real-time PCR (rtPCR) and nested PCR (nPCR) to evaluate the detection of T. gondii in naturally infected cats. Biological samples of Toxoplasma-seropositive cats were assayed for detection of T. gondii DNA – extracted by both the lysis buffer and proteinase K (LB proteinase K) method and the acid guanidinium thiocyanate (GuSCN) method – using rtPCR and nPCR. T. gondii DNA was detected by nPCR in 43.6% and 40.

An analysis of the viscoelastic behavior did not reveal any real differences in molecular coupling around the beta-transition of PP with the addition of the MAPP copolymer. At low addition levels, MAPP does not appear to have a significant impact on the viscoelastic properties of the polymer blend. (0 2008 Wile), Periodicals, Inc. J Appl Polym Sci 111: 753-758, 2009″
“Study Design. Multicenter randomized, double-blind, simulated therapy-controlled trial in a cohort

of patients with acute low back pain (LBP) due to lumbar disc herniation (LDH).

Objective. To assess the benefit of intramuscular-paravertebral injections of an oxygen-ozone ACY-738 ic50 (O(2)O(3)) mixture.

Summary of Background Data. Recent findings have shown that O(2)O(3) therapy can be used to treat LDH that fails to respond to conservative management. However, these findings are based on intradiscal/intraforaminal O(2)O(3) injection, whereas intramuscular-paravertebral injection is the technique used most in clinical practice in Italy and other Western countries.

Methods. Sixty patients suffering from acute LBP caused by LDH was randomized to an intramuscular O(2)O(3) or control group. Patients were observed up to assess pain intensity, LBP-related disability, and drug intake ( 15 [V2] and 30 [V3]

days after treatment started, and 2 weeks [V4], and 3 [V5] and 6 [V6] months after treatment ended).

Results.

A significant Mcl-1 apoptosis difference between selleckchem the 2 groups in the percentage of cases who had become pain-free (61% vs. 33%, P < 0.05) was observed at V6. Patients who received O(2)O(3) had a lower mean pain score than patients who received simulated therapy throughout the observation period. A significant improvement was observed in LBP-related disability in the study group patients when compared with the control group patients. Active O(2)O(3) therapy was followed by a significantly lower number of days on nonsteroidal anti-inflammatory drugs at V2 and V3 and by a lower number of days at V4. No adverse events were reported.

Conclusion. Treatment of LBP and sciatica is a major concern. Although the natural history of acute LBP is often self-limiting, conservative therapies are not always effective; in such cases, O(2)O(3) intramuscular lumbar paravertebral injections, which are minimally invasive, seem to safely and effectively relieve pain, as well as reduce both disability and the intake of analgesic drugs.”
“BACKGROUND Prediction of whether postoperative wound healing will result in a hypertrophic scar or keloid is difficult. Diverse treatment options have been developed in an effort to prevent excessive scar formation. OBJECTIVE To evaluate the efficacy and safety of a 532-nm potassium titanyl phosphate (KTP) laser in the prevention of scar formation after total thyroidectomy.

49; 95% CI: [0.29-0.81]; p = 0.004). Leucopoenia (p = 0.001), thrombocytopenia (p = 0.017) and diarrhea (p = 0.002) occurred more frequently in the experimental group. Reduced-dose tacrolimus with mycophenolate mofetil reduces the occurrence of renal dysfunction and the risk of graft rejection. This immunosuppressive regimen could replace full-dose tacrolimus in adult liver transplantation.”
“Temporal patterns of brain interstitial amino acids after subarachnoid haemorrhage (SAH) were studied in relation to energy metabolite levels

and to the severity of the initial global ischaemia as reflected by the level of consciousness at admission.

Intracerebral microdialysis was used to measure brain interstitial amino acids and the energy metabolites glucose, lactate, and pyruvate during five days in 19 patients.

Patients who were conscious (n = 11) were compared to those who were unconscious on admission buy AZD1208 (n = 8).

Eight non-transmitter amino acids (alanine, aspargine, glutamine, isoleucine, leucine, phenylalanine, serine and tyrosine), as well as glycine and pyruvate showed a pattern of increasing concentrations starting at 60-70 h after the onset of SAH. The conscious patients showed more pronounced elevations of non-transmitter amino acids, glycine, taurine and pyruvate www.selleckchem.com/products/xmu-mp-1.html compared to the unconscious patient group. Pyruvate levels were initially critically low for all patients, then normalised in the conscious patients but remained low in the unconscious group.

There was an increase of the cerebral interstitial levels of non-transmitter amino acids and glycine which correlated temporally to pyruvate levels, more pronounced in patients conscious on admission. Pyruvate levels in these patients normalised, but remained reduced in the unconscious patients. The increase of the non-transmitter amino acids and glycine could reflect an increased amino acid turnover in an attempt at repairing the injured Selleckchem 5-Fluoracil brain, which could have been hampered by the lower pyruvate levels. Interstitial pyruvate may be a useful marker of the energy metabolic situation in the acutely injured brain.”
“Three

new triterpenoid derivatives, 3-O-beta-D-glucopyranosyl-20(S)-protopanaxtriol (1), 3-formyloxy-20-O-beta-D-glucopyranosyl-20(S)-protopanaxtriol (2) and 26-hydroxyl-24(E)-20(S)-protopanaxtriol (3), along with six known ginsenosides, were isolated from leaves of Panax ginseng. Their structures were established on the basis of spectral analysis (IR, 1D and 2D NMR, HRESI-MS). Compounds 1-3 exhibited various degree of cytotoxicity towards human A549 pulmonary carcinoma cells and Hep3B hepatoma cells.”
“A combined experimental, theoretical, and numerical investigation of dynamic growth and coalescence of drilled voids in pure copper sheets was performed to visualize void growth and coalescence in a controlled matter.