The carbon nanotube has unique electronic structures which as car

The carbon nanotube has unique electronic structures which as carbon nanotube electrochemical sensor probability makes simpler the investigation of redox-active proteins and amino acids allowing cell monitoring in engineered tissues. In one study, MWNTs were conjugated with platinum microparticles and were able to sense thiols including amino acids such as glutathione and L-cysteine in rat [81]. The matrix of cells plays

an important role in tissue engineering. While accepted synthetic polymers, for example, PLGA and PLA have been employed for tissue engineering, they lack the required mechanical Tariquidar research buy strength and cannot simply be functionalized in contradiction of carbon nanotubes which can be voluntarily functionalized. Thus, carbon nanotubes have potential for use as tissue scaffolds and can provide the required structural reinforcement, but the main disadvantage of carbon nanotubes is that they are not biodegradable. Combination of polymer by dissolving a AZD6738 concentration desired portion of carbon nanotubes

into a polymer, significant enhancements in the mechanical strength of the composite has been detected. MWNTs combined with chitosan illustrated significant advancement in mechanical properties compared with only chitosan [82]. The SWNT blended collagen improves smooth muscle cell growth [83–89]. Cancer cell identification Nanodevices are being created that have a potential to develop cancer treatment, detection, and diagnosis.

Nanostructures can be so small (less than 100 nm) that the body possibly will clear them too quickly for them to be efficient in imaging or detection and so can enter cells and the organelles inside them to interact with DNA and proteins. Castillo et al., by using a peptide nanotube-folic acid modified graphene electrode, improve detection of human cervical cancer cells overexpressing folate receptors [90–96]. Since a large amount of cancers are asymptomatic throughout their early stage and distinct morphologic modifications are absent selleckchem in the majority of neoplastic disorders in early stage, consequently traditional clinical cancer imaging methods, for example, X-ray, CT, and MRI, do not BMS202 supplier acquire adequate spatial resolution for detection of the disease in early stage. The imaging studies with SWCNTs have thrived over the past few years. Hong et al. [97] evaluated the molecular imaging with SWNTs and evaluated the combined Gd3 + -functionalized SWCNTs when applied to MRI, and high resolution and good tissue penetration were achieved. Combination of radioisotopes labeled SWCNTs with radionuclide based imaging techniques (PET and SPECT) can improve the tissue penetration, sensitivity, and medium resolution.

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