The authors found only one case report of favorable outcome after laparostomy as a treatment of wound dehiscence in pregnant women [7]. In the present case leaving the abdomen open was a deliberate intraoperative decision. We adopted the principles of damage control surgery consisting of planned subsequent delayed explorations after the primary debridement and necrotic bowel resections. It was shown that temporary dressing with vacuum pack is a safe, well

tolerated technique [8]. The disadvantage of laparostomy is the difficulty of the subsequent fascial closure. Abdominal sepsis and trauma seems associated with higher rate of fascial closure failure and consecutive incisional hernia. Among many techniques developed for open abdomen management, vacuum assisted buy CH5424802 closure (VAC) allows currently the best results in term of primary abdominal wall closure [9]. In some series, using VAC protocols, complete fascial closure rate was achieved in 100% [10]. In abdomen with constantly growing gravid uterus and low intra-abdominal pressures requirements, primary closure appears to be a particularly Ispinesib clinical trial challenging task. It is nevertheless a key endpoint in a pregnant woman,

in order to protect the foetus and to assure a vaginal delivery. The present case report contributes to the rational that decision making in severe abdominal surgical emergency in pregnant women should respect the same principles and use the same techniques as in non-pregnant patient. The decision process should not be delayed by pregnancy. The management of acute abdomen by laparostomy during SGC-CBP30 mouse pregnancy is feasible, and may be associated with a good outcome for both the mother and the child. Consent Written informed consent was obtained from the patient for publication of this case report and ADAMTS5 any accompanying images. References 1. Sharp HT: The acute abdomen during pregnancy. Clin Obstet Gynecol 2002,45(2):405–13.CrossRefPubMed 2. Kilpatrick CC, Orejuela FJ: Management of the acute abdomen in pregnancy: a review. Curr Opin Obstet Gynecol 2008,20(6):534–9.CrossRefPubMed 3. Cohen-Kerem R, Railton C,

Oren D, Lishner M, Koren G: Pregnancy outcome following non-obstetric surgical intervention. Am J Surg 2005,190(3):467–73.CrossRefPubMed 4. Rizzo AG: Laparoscopic surgery in pregnancy: long-term follow-up. Laparoendosc Adv Surg Tech A 2003,13(1):11–5.CrossRef 5. Augustin G, Majerovic M: Non-obstetrical acute abdomen during pregnancy. Eur J Obstet Gynecol Reprod Biol 2007,131(1):4–12.CrossRefPubMed 6. Gecelter G, Fahoum B, Gardezi S, Schein M: Abdominal compartment syndrome in severe acute pancreatitis: an indication for a decompressing laparotomy? Dig Surg 2002,19(5):402–4.CrossRefPubMed 7. Shapiro SB, Mumme DE: Use of Negative Pressure Wound Therapy in the Management of Wound Dehiscence in a Pregnant Patient. Wounds 2008., (2): 8. Cheatham ML, Safcsak K: Longterm impact of abdominal decompression: a prospective comparative analysis.