2002;15:542-545). We report an African-American patient who presented with progressive back and chest pain of recent onset, numbness, tingling, and gait disturbance due to T3 paraplegia secondary to ossified ligamentum flavum resulting in thoracic spinal stenosis. On cross-sectional imaging, there was cord effacement at multiple levels, most pronounced at T10. The patient required emergency laminectomies, which allowed him to recover significant function. This case presentation should heighten physician awareness to this unusual clinical entity, since early diagnosis and timely surgical intervention can prevent permanent neurologic deficits.”
“Background: Framingham

Study data Selleckchem GDC 0068 indicate an incremental risk of cardiovascular death in relation to low exercise capacity in women. The reason for death is still not clear.\n\nMethods: QT restitution properties in 80 middle-aged women were investigated to confirm whether the cardiac restitution property was affected by the exercise capacity. Exercise tests were performed according to the Bruce protocol. Seventy cases were divided into the low exercise capacity group (LEC group) and high-exercise capacity Smoothened Agonist mw group (HEC group) by median exercise capacities. Sequential QT intervals and their preceding TQ intervals

were measured, and the QT restitution curve (QTRC) was constructed. Two exponential equations were used to match the data and calculate the maximum slope (Smax) of QTRC, respectively.\n\nResults:

With elevation in the exercise level, the women in the LEC group had a higher change rate of QT intervals (41 +/- 10 vs 29 +/- 3 ms/Met, P = .001) and TQ intervals (46 +/- 12 vs 41 +/- 7 ms/Met, P = .046); and the ratio of QT interval alterations to TQ interval alterations increased (0.41 +/- 0.09 vs 0.36 +/- 0.07, P = .003). The Smax of the QTRC in the LEC group was higher than that in the HEC group (1.43 +/- 0.44 vs 1.13 +/- 0.34, P = .002). There was an inverse Selleck Repotrectinib relationship between Smax and exercise capacity (r = -0.43, P = .001).\n\nConclusion: Middle-aged women with low exercise capacity have steeper QTRCs than those with high exercise capacity, denoting a more unstable alternation of QT interval with elevation in exercise level. (c) 2011 Elsevier Inc. All rights reserved.”
“In the Indian Ocean, bigeye tuna supports one of the most important fisheries in the world. This fishery mainly consists of two components: longline and purse seine fisheries. Evidence of overfishing and stock depletion of bigeye tuna calls for an evaluation of alternative management strategies. Using an age-structured operating model, parameterized with the results derived in a recent stock assessment, we evaluated the effectiveness of applying constant fishing mortality (CF) and quasi-constant fishing mortality (QCF) strategies to reduce fishing effort of purse seining with fish aggregating devices (FADs) at different rates.