Esophageal varices or gastropathy portal hypertension are common causes of upper gastrointestinal bleeding in Indonesia. The aim of study was to determine the endoscopic finding in patient with upper gastrointestinal bleeding

in Awal Bros Hospital, Riau, Indonesia. Methods: This retrospective study was conducted in 1,032 patients with upper gastrointestinal bleeding who had underwent upper gastrointestinal endoscopy at private referral Awal Bros Hospital, Pekanbaru between January 2009 and December selleck chemical 2013. Results: There were 1032 eligible patients consisting of 577 (55.91%) males and 455 females (44.09%) ranged from 17–87 years old. The greatest occurrence was at the age group 50–59 years (23.63%). The endoscopy results showed that the most common cause of bleeding was gastropathy NSAID, which occurred in 552 (53.41%) cases, the other finding were 283 (27.47%) cases of gastric ulcer, 95 (9.27%) cases of esophageal varices, 54 (5.23%) cases of duodenal ulcers, 34 (3.29%) cases of erosive gastritis and 14 (1.41%) cases of gastric neoplasm. Conclusion: The greatest occurrence of upper gastrointestinal

bleeding between January 2009 and December 2013 in Awal Bros Hospital was at the age group 50–59 years and male. The gastropathy NSAID was the most common cause in this study. This finding is different compared with R428 the etiology in Indonesia which esophageal varices or gastropathy portal hypertension were the most common cause. Key Word(s): 1. endoscopic finding;

2. upper gastrointestinal bleeding; 3. gastropathy NSAID Presenting Author: RAVISHANKAR ASOKKUMAR Additional Authors: JASON CHANG PE Corresponding Author: RAVISHANKAR ASOKKUMAR Affiliations: Singapore General Hospital Objective: Portal hypertension(PHT) can occur in myeloproliferative disease(MPD) either from spleno-portal venous thrombosis or due to increased portal inflow from MPD. Our study aims to describe the association and outcome of PHT in MPD. Methods: We reviewed the records of 18 patients with MPD referred for gastroenterology evaluation at our hospital from 1999–2013. Demographics, clinical presentation, endoscopy, radiology findings and treatment outcomes were analyzed. Results: Median age learn more at presentation was 52(range 41–75)years. Fifteen(83%) were Chinese and 3(17%) Malay. Main presenting symptoms were abdominal pain(39%), variceal bleeding(33%) and thrombocytopenia(22%).Type of MPD included myelofibrosis(39%), essential thrombocytosis(27%), polycythemia rubra vera(22%) and others(11%). MPD was diagnosed by positive JAK-2 mutation or bone marrow analysis. All had significant splenomegaly with a mean spleen size(SS)of 18.4(±3.7)cm. Liver function was normal in all patients. Mean liver stiffness was 9.6 ± 3.1 kPa in 11 patients who underwent Fibroscan®. Radiological imaging showed splenomegaly and collaterals without features of chronic liver disease in all patients.